This is a list and brief description of courses offered by faculty
in the Department of Neurobiology and related faculty in the Biological
Sciences Division. Most of the course descriptions are taken from the University of Chicago Course Catalog.
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NPHP 33600
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Cell Signaling (=CPHY 33600)
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Autumn
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Palfrey
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Cells in the body communicate with each other by a
variety of extracellular signals (e.g., hormones and
neurotransmitters) that are disseminated locally or in the
bloodstream to distant targets. What happens when these signals are
received by the target cells? The subject matter of this course
considers the wide variety of intracellular mechanisms that, when
activated, change cell behavior. Both general and specific aspects of
intracellular signaling are covered in the course, the latter
including detailed discussions of receptors, G-proteins, cyclic
nucleotides, calcium and calcium-binding proteins, phosphoinositides,
protein kinases, and phosphatases. C. Prereq: BIOS 20200 and 20181, or
BIOS 20191.
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NPHP 31800
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Cellular Neurobiology (=NURB 31800)
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Autumn
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Lloyd
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The cell biology of neurons is considered, with emphasis
on intracellular and intercellular communication and regulation.
Simple neuronal systems, especially those of invertebrates, are
analyzed from a functional viewpoint.
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DVBI 35800
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Developmental neurobiology and brain plasticity
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Winter
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Grove
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Topics include neural induction, early patterning of the
central nervous system, axonguidance and neuronal migration, the
development of brain activity, and the mechanisms of plasticity that
fine-tune brain function. Approaches will range from molecular to
cellular to systems neurobiology. Focus will be on the vertebrate CNS
but attention will be given to important lessons from invertebrate
systems.
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NURB 32400
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Synaptic physiology
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McGehee, Fox
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NURB 30500
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Medical neurobiology
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Staff
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NPHP 33200
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Ionic Channels and Excitable Membranes (=CPHY 33200)
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Winter
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Nelson, Hanck
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A review of the voltage-gated and ligand-gated channels, including
the functional role(s) of the channels in cell behavior and
biophysical aspects of ion transport through channels. Correlation is
made between known channel protein structure and channel functional
characteristics, including gating, block and drug-related changes in
channel current kinetics.
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NURB 31600
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Survey of systems neuroscience
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Autumn
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Ragsdale and Staff
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This lab-centered course teaches students the
fundamental principles of mammalian neuroanatomy. Students learn the
major structures and the basic circuitry of the CNS and PNS. Somatic,
visual, auditory, vestibular and olfactory sensory systems are presented
in particular depth. In addition, students select two courses in
pharmacology.
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NPHP 32200
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Molecular Neurobiology (=NURB 32200)
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Green and Popko
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Current research in the molecular biology of the nervous
system, i.e., the structure and function of macromolecules that
control, propagate, and elicit neural signaling. Topics covered
include (1) structural elements of neurons and glia; (2) structure
and function of the synapse; (3) aspects of the molecular basis of
neural signaling; and (4) gene expression in neural systems. Lectures
draw on current journal literature to present a state-of-the-art
background of the topic, the current questions being explored, as
well as problems and aspects.
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NPHP 32800
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Neuropsychopharmacology II
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Vezina
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Effects of drugs on behavior; emphasis on the functional
contribution of brain neurotransmitter systems.
Other courses offered by the Dept of Neurobiology, Pharmacology and
Physiology
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NURB 33400
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Genetics in Neuropharmacology
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Zhuang
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This course focuses on diverse genetic approaches in
pharmacology research. Topics are organized by genetic approaches
including knockout, transgenic, knock-in, tissue-specific knockout,
inducible strategies, forward genetics, pharmacogenomics and gene
therapy. The selection of papers aims to cover different
neurotransmitter systems and signaling pathways.
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Research credit (varied units) for research undertaken
by graduate students under the guidance of a faculty member of the
Department of Neurobiology, Pharmacology and Physiology.
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